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O-GlcNAcylation of α-Synuclein at Serine 87 Reduces Aggregation without Affecting Membrane Binding

The aggregation of neurodegenerative-disease associated proteins can be affected by many factors, including a variety of post-translational modifications. One such modification, O-GlcNAcylation, has been found on some of these aggregation prone proteins, including α-synuclein, the major protein that...

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Detalles Bibliográficos
Publicado en:ACS Chem Biol
Main Authors: Lewis, Yuka E., Galesic, Ana, Levine, Paul M., De Leon, Cesar A., Lamiri, Natalie, Brennan, Caroline K., Pratt, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607117/
https://ncbi.nlm.nih.gov/pubmed/28195695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00113
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