Histone demethylases Kdm6ba and Kdm6bb redundantly promote cardiomyocyte proliferation during zebrafish heart ventricle maturation

Trimethylation of lysine 27 on histone 3 (H3K27me3) by the Polycomb repressive complex 2 (PRC2) contributes to localized and inherited transcriptional repression. Kdm6b (Jmjd3) is a H3K27me3 demethylase that can relieve repression-associated H3K27me3 marks, thereby supporting activation of previousl...

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Udgivet i:Dev Biol
Main Authors: Akerberg, Alexander A., Henner, Astra, Stewart, Scott, Stankunas, Kryn
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607060/
https://ncbi.nlm.nih.gov/pubmed/28372944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2017.03.030
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