Neuroprotection with hypothermia and allopurinol in an animal model of hypoxic-ischemic injury: Is it a gender question?

BACKGROUND: Hypoxic-ischemic encephalopathy (HIE) is one of the most important causes of neonatal brain injury. Therapeutic hypothermia (TH) is the standard treatment for term newborns after perinatal hypoxic ischemic injury (HI). Despite this, TH does not provide complete neuroprotection. Allopurin...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Rodríguez-Fanjul, Javier, Durán Fernández-Feijóo, Cristina, Lopez-Abad, Míriam, Lopez Ramos, Maria Goretti, Balada Caballé, Rafael, Alcántara-Horillo, Soledad, Camprubí Camprubí, Marta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606927/
https://ncbi.nlm.nih.gov/pubmed/28931035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184643
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