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Mutational analysis of BRCA1 and BRCA2 genes in Peruvian families with hereditary breast and ovarian cancer

BACKGROUND: Breast cancer is one of the most prevalent malignancies in the world. In Peru, breast cancer is the second cause of death among women. Five to ten percent of patients present a high genetic predisposition due to BRCA1 and BRCA2 germline mutations. METHODS: We performed a comprehensive an...

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Publicat a:Mol Genet Genomic Med
Autors principals: Buleje, Jose, Guevara‐Fujita, Maria, Acosta, Oscar, Huaman, Francia D. P., Danos, Pierina, Murillo, Alexis, Pinto, Joseph A., Araujo, Jhajaira M., Aguilar, Alfredo, Ponce, Jaime, Vigil, Carlos, Castaneda, Carlos, Calderon, Gabriela, Gomez, Henry L., Fujita, Ricardo
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606899/
https://ncbi.nlm.nih.gov/pubmed/28944232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.301
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