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RETRACTED: Structural analysis of BRCA1 reveals modification hotspot

Cancer cells afflicted with mutations in the breast cancer susceptibility protein (BRCA1) often suffer from increased DNA damage and genomic instability. The precise manner in which physical changes to BRCA1 influence its role in DNA maintenance remains unclear. We used single-particle electron micr...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Liang, Yanping, Dearnaley, William J., Varano, A. Cameron, Winton, Carly E., Gilmore, Brian L., Alden, Nick A., Sheng, Zhi, Kelly, Deborah F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606707/
https://ncbi.nlm.nih.gov/pubmed/28948225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1701386
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