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Current View in Platinum Drug Mechanisms of Peripheral Neurotoxicity

Peripheral neurotoxicity is the dose-limiting factor for clinical use of platinum derivatives, a class of anticancer drugs which includes cisplatin, carboplatin, and oxaliplatin. In particular cisplatin and oxaliplatin induce a severe peripheral neurotoxicity while carboplatin is less neurotoxic. Th...

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Detalhes bibliográficos
Publicado no:Toxics
Main Authors: Chiorazzi, Alessia, Semperboni, Sara, Marmiroli, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606682/
https://ncbi.nlm.nih.gov/pubmed/29051466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxics3030304
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