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Treatment With Tafamidis Slows Disease Progression in Early-Stage Transthyretin Cardiomyopathy

BACKGROUND: Transthyretin cardiomyopathy (TTR-CM) is a progressive, fatal disease caused by the accumulation of misfolded transthyretin (TTR) amyloid fibrils in the heart. Tafamidis is a kinetic stabilizer of TTR that inhibits misfolding and amyloid formation. METHODS: In this post hoc analysis, dat...

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Detalhes bibliográficos
Publicado no:Clin Med Insights Cardiol
Main Authors: Sultan, Marla B, Gundapaneni, Balarama, Schumacher, Jennifer, Schwartz, Jeffrey H
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606341/
https://ncbi.nlm.nih.gov/pubmed/28951660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1179546817730322
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