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Toll like Receptor 2 engagement on CD4(+) T cells promotes TH9 differentiation and function

We have recently demonstrated that mycobacterial ligands engage Toll like receptor 2 (TLR2) on CD4(+) T cells and up-regulate T-cell receptor (TCR) triggered Th1 responses in vitro and in vivo. To better understand the role of T-cell expressed TLR2 on CD4(+) T cell differentiation and function, we c...

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Pubblicato in:Eur J Immunol
Autori principali: Karim, Ahmad Faisal, Reba, Scott M., Li, Qing, Boom, W. Henry, Rojas, Roxana E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606324/
https://ncbi.nlm.nih.gov/pubmed/28665005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646846
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