Loading...
Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase
The ABCs of PXE Pseudoxanthoma elasticum (PXE) is a genetic disorder caused by mutations in ABCC6 that is characterized by calcium deposition outside of the skeletal system, specifically in the blood vessels, skin, and eyes. Using patient-derived fibroblasts and genetic knockout mouse models, Ziegle...
Saved in:
| Published in: | Sci Transl Med |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5606141/ https://ncbi.nlm.nih.gov/pubmed/28592560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aal1669 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|