Generation of special autosomal dominant polycystic kidney disease iPSCs with the capability of functional kidney-like cell differentiation

BACKGROUND: Human induced pluripotent stem cells (iPSCs) have been verified as a powerful cell model for the study of pathogenesis in hereditary disease. Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations of PKD or non-PKD genes. The pathogenesis of ADPKD remains unexplored...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Huang, Jiahui, Zhou, Shumin, Niu, Xin, Hu, Bin, Li, Qing, Zhang, Feng, Zhang, Xue, Cai, Xiujuan, Lou, Yuanlei, Liu, Fen, Xu, Chenming, Wang, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606115/
https://ncbi.nlm.nih.gov/pubmed/28927462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0645-8
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