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p53: key conductor of all anti-acne therapies
This review based on translational research predicts that the transcription factor p53 is the key effector of all anti-acne therapies. All-trans retinoic acid (ATRA) and isotretinoin (13-cis retinoic acid) enhance p53 expression. Tetracyclines and macrolides via inhibiting p450 enzymes attenuate ATR...
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| Udgivet i: | J Transl Med |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5606086/ https://ncbi.nlm.nih.gov/pubmed/28927457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1297-2 |
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