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Variation in loss of immunity shapes influenza epidemics and the impact of vaccination

BACKGROUND: Protective antibody immunity against the influenza A virus wanes in 2–7 years due to antigenic drift of the virus’ surface proteins. The duration of immune protection is highly variable because antigenic evolution of the virus is irregular. Currently, the variable nature of the duration...

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Veröffentlicht in:BMC Infect Dis
Hauptverfasser: Woolthuis, Rutger G., Wallinga, Jacco, van Boven, Michiel
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606000/
https://ncbi.nlm.nih.gov/pubmed/28927373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-017-2716-y
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