Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank

Background: Cognitive ability is a heritable trait with a polygenic architecture, for which several associated variants have been identified using genotype-based and candidate gene approaches. Haplotype-based analyses are a complementary technique that take phased genotype data into account, and pot...

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Pubblicato in:Wellcome Open Res
Autori principali: Howard, David M., Adams, Mark J., Clarke, Toni-Kim, Wigmore, Eleanor M., Zeng, Yanni, Hagenaars, Saskia P., Lyall, Donald M., Thomson, Pippa A., Evans, Kathryn L., Porteous, David J., Nagy, Reka, Hayward, Caroline, Haley, Chris S., Smith, Blair H., Murray, Alison D., Batty, G. David, Deary, Ian J., McIntosh, Andrew M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: F1000Research 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605947/
https://ncbi.nlm.nih.gov/pubmed/28989979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.12171.1
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