Anti-apoptotic and myocardial protective effects of ethyl pyruvate after regional ischaemia/reperfusion myocardial damage in an in vivo rat model

INTRODUCTION: The integration of reactive oxygen species is strongly associated with important pathophysiological mechanisms that mediate myocardial ischaemia/reperfusion (I/R) damage. Pyruvate is an efficacious scavenger of reactive oxygen species and a previous study has shown that ethyl pyruvate...

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Publicat a:Singapore Med J
Autors principals: Shim, Haeng Seon, Lee, Wang Gyu, Kim, Yeon A, Han, Jeong Yeol, Park, Miyeong, Song, Yun Gyu, Kim, Joon Soo, Shin, Il-Woo
Format: Artigo
Idioma:Inglês
Publicat: Singapore Medical Association 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605828/
https://ncbi.nlm.nih.gov/pubmed/27995262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.11622/smedj.2016190
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