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cis-Tetrachlorido-bis(indazole)osmium(IV) and its osmium(III) analogues: paving the way towards the cis-isomer of the ruthenium anticancer drugs KP1019 and/or NKP1339

The relationship between cis-trans isomerism and anticancer activity has been mainly addressed for square-planar metal complexes, in particular, for platinum(II), e.g., cis- and trans-[PtCl(2)(NH(3))(2)], and a number of related compounds, of which, however, only cis-counterparts are in clinical use...

詳細記述

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書誌詳細
出版年:Dalton Trans
主要な著者: Büchel, Gabriel E., Kossatz, Susanne, Sadique, Ahmad, Rapta, Peter, Zalibera, Michal, Bucinsky, Lukas, Komorovsky, Stanislav, Telser, Joshua, Eppinger, Jörg, Reiner, Thomas, Arion, Vladimir B.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605806/
https://ncbi.nlm.nih.gov/pubmed/28850133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7dt02194a
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