A pore-forming protein implements VLR-activated complement cytotoxicity in lamprey

Lamprey is a basal vertebrate with a unique adaptive immune system, which uses variable lymphocyte receptors (VLRs) for antigen recognition. Our previous study has shown that lamprey possessed a distinctive complement pathway activated by VLR. In this study, we identified a natterin family member–la...

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Bibliografski detalji
Izdano u:Cell Discov
Glavni autori: Wu, Fenfang, Feng, Bo, Ren, Yong, Wu, Di, Chen, Yue, Huang, Shengfeng, Chen, Shangwu, Xu, Anlong
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605768/
https://ncbi.nlm.nih.gov/pubmed/28944078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2017.33
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