Exercise-induced irisin in bone and systemic irisin administration reveal new regulatory mechanisms of bone metabolism

Irisin is a polypeptide hormone derived from the proteolytic cleavage of fibronectin-type III domain-containing 5 (FNDC5) protein. Once released to circulation upon exercise or cold exposure, irisin stimulates browning of white adipose tissue (WAT) and uncoupling protein 1 (UCP1) expression, leading...

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Published in:Bone Res
Main Authors: Zhang, Jin, Valverde, Paloma, Zhu, Xiaofang, Murray, Dana, Wu, Yuwei, Yu, Liming, Jiang, Hua, Dard, Michel M, Huang, Jin, Xu, Zhiwei, Tu, Qisheng, Chen, Jake
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605767/
https://ncbi.nlm.nih.gov/pubmed/28944087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2016.56
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