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Systems Approach Reveals Nuclear Factor Erythroid 2-Related Factor 2/Protein Kinase R Crosstalk in Human Cutaneous Leishmaniasis

Leishmania parasites infect macrophages, causing a wide spectrum of human diseases, from cutaneous to visceral forms. In search of novel therapeutic targets, we performed comprehensive in vitro and ex vivo mapping of the signaling pathways upstream and downstream of antioxidant transcription factor...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Vivarini, Áislan de Carvalho, Calegari-Silva, Teresa Cristina, Saliba, Alessandra Mattos, Boaventura, Viviane Sampaio, França-Costa, Jaqueline, Khouri, Ricardo, Dierckx, Tim, Dias-Teixeira, Karina Luiza, Fasel, Nicolas, Barral, Aldina Maria Prado, Borges, Valéria Matos, Van Weyenbergh, Johan, Lopes, Ulisses Gazos
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605755/
https://ncbi.nlm.nih.gov/pubmed/28959260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01127
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