Systems Approach Reveals Nuclear Factor Erythroid 2-Related Factor 2/Protein Kinase R Crosstalk in Human Cutaneous Leishmaniasis

Leishmania parasites infect macrophages, causing a wide spectrum of human diseases, from cutaneous to visceral forms. In search of novel therapeutic targets, we performed comprehensive in vitro and ex vivo mapping of the signaling pathways upstream and downstream of antioxidant transcription factor...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Vivarini, Áislan de Carvalho, Calegari-Silva, Teresa Cristina, Saliba, Alessandra Mattos, Boaventura, Viviane Sampaio, França-Costa, Jaqueline, Khouri, Ricardo, Dierckx, Tim, Dias-Teixeira, Karina Luiza, Fasel, Nicolas, Barral, Aldina Maria Prado, Borges, Valéria Matos, Van Weyenbergh, Johan, Lopes, Ulisses Gazos
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605755/
https://ncbi.nlm.nih.gov/pubmed/28959260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01127
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