Interrogating islets in health and disease with single-cell technologies

BACKGROUND: Blood glucose levels are tightly controlled by the coordinated actions of hormone-producing endocrine cells that reside in pancreatic islets. Islet cell malfunction underlies diabetes development and progression. Due to the cellular heterogeneity within islets, it has been challenging to...

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Publicado en:Mol Metab
Main Authors: Carrano, Andrea C., Mulas, Francesca, Zeng, Chun, Sander, Maike
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2017
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605723/
https://ncbi.nlm.nih.gov/pubmed/28951823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.04.012
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