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Enabling stop codon read-through translation in bacteria as a probe for amyloid aggregation

Amyloid aggregation of the eukaryotic translation terminator eRF3/Sup35p, the [PSI (+)] prion, empowers yeast ribosomes to read-through UGA stop codons. No similar functional prion, skipping a stop codon, has been found in Escherichia coli, a fact possibly due to the efficient back-up systems found...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Molina-García, Laura, Giraldo, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605706/
https://ncbi.nlm.nih.gov/pubmed/28928456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12174-0
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