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Dimerization regulates both deaminase-dependent and deaminase-independent HIV-1 restriction by APOBEC3G
APOBEC3G (A3G) is a human enzyme that inhibits human immunodeficiency virus type 1 (HIV-1) infectivity, in the absence of the viral infectivity factor Vif, through deoxycytidine deamination and a deamination-independent mechanism. A3G converts from a fast to a slow binding state through oligomerizat...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5605669/ https://ncbi.nlm.nih.gov/pubmed/28928403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00501-y |
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