The Significance of Discordant Serology in Chagas Disease: Enhanced T-Cell Immunity to Trypanosoma cruzi in Serodiscordant Subjects

BACKGROUND: Subjects are considered infected with Trypanosoma cruzi when tested positive by at least two out of three serological tests, whereas a positive result in only one of up to three tests is termed “serodiscordant” (SD). Assessment of parasite-specific T-cell responses may help discriminate...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Castro Eiro, Melisa D., Alvarez, María G., Cooley, Gretchen, Viotti, Rodolfo J., Bertocchi, Graciela L., Lococo, Bruno, Albareda, María C., De Rissio, Ana M., Natale, María A., Parodi, Cecilia, Tarleton, Rick L., Laucella, Susana A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605634/
https://ncbi.nlm.nih.gov/pubmed/28966620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01141
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