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Allele Age Under Non-Classical Assumptions is Clarified by an Exact Computational Markov Chain Approach

Determination of the age of an allele based on its population frequency is a well-studied problem in population genetics, for which a variety of approximations have been proposed. We present a new result that, surprisingly, allows the expectation and variance of allele age to be computed exactly (wi...

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Опубликовано в: :Sci Rep
Главные авторы: De Sanctis, Bianca, Krukov, Ivan, de Koning, A. P. Jason
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605573/
https://ncbi.nlm.nih.gov/pubmed/28928413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12239-0
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