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T-bet-dependent NKp46(+) innate lymphoid cells regulate the onset of T(H)17-induced neuroinflammation

The transcription factor T-bet has been linked to increased susceptibility to systemic and organ-specific autoimmunity, but the mechanism by which T-bet expression promotes neuroinflammation remains unknown. In this study, we demonstrate a cardinal role for T-bet-dependent NKp46(+) innate lymphoid c...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Kwong, Brandon, Rua, Rejane, Gao, Yuanyuan, Flickinger, John, Wang, Yan, Kruhlak, Michael J., Zhu, Jinfang, Vivier, Eric, McGavern, Dorian B., Lazarevic, Vanja
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605431/
https://ncbi.nlm.nih.gov/pubmed/28805812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3816
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