Chlamydia trachomatis Prevents Apoptosis Via Activation of PDPK1-MYC and Enhanced Mitochondrial Binding of Hexokinase II

The intracellular human bacterial pathogen Chlamydia trachomatis pursues effective strategies to protect infected cells against death-inducing stimuli. Here, we show that Chlamydia trachomatis infection evokes 3-phosphoinositide-dependent protein kinase-1 (PDPK1) signaling to ensure the completion o...

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發表在:EBioMedicine
Main Authors: Al-Zeer, Munir A., Xavier, Audrey, Abu Lubad, Mohammad, Sigulla, Janine, Kessler, Mirjana, Hurwitz, Robert, Meyer, Thomas F.
格式: Artigo
語言:Inglês
出版: Elsevier 2017
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605330/
https://ncbi.nlm.nih.gov/pubmed/28803120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.08.005
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