Scavenging of reactive oxygen species by astaxanthin inhibits epithelial–mesenchymal transition in high glucose-stimulated mesothelial cells

BACKGROUND: High glucose concentrations influence the functional and structural development of the peritoneal membrane. We previously reported that the oral administration of astaxanthin (AST) suppressed peritoneal fibrosis (PF) as well as inhibited oxidative stress, inflammation, and epithelial–mes...

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Veröffentlicht in:PLoS One
Hauptverfasser: Hara, Kazuaki, Hamada, Chieko, Wakabayashi, Keiichi, Kanda, Reo, Kaneko, Kayo, Horikoshi, Satoshi, Tomino, Yasuhiko, Suzuki, Yusuke
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604950/
https://ncbi.nlm.nih.gov/pubmed/28926603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184332
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