Impact of genotyping errors on statistical power of association tests in genomic analyses: A case study

A key step in genomic studies is to assess high throughput measurements across millions of markers for each participant’s DNA, either using microarrays or sequencing techniques. Accurate genotype calling is essential for downstream statistical analysis of genotype-phenotype associations, and next ge...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Hou, Lin, Sun, Ning, Mane, Shrikant, Sayward, Fred, Rajeevan, Nallakkandi, Cheung, Kei-Hoi, Cho, Kelly, Pyarajan, Saiju, Aslan, Mihaela, Miller, Perry, Harvey, Philip D., Gaziano, J. Michael, Concato, John, Zhao, Hongyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604789/
https://ncbi.nlm.nih.gov/pubmed/28019059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22027
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