Design of the PF-ILD trial: a double-blind, randomised, placebo-controlled phase III trial of nintedanib in patients with progressive fibrosing interstitial lung disease

600 patients aged ≥18 years will be randomised in a 1:1 ratio to nintedanib or placebo. Patients with diagnosis of IPF will be excluded. The study population will be enriched with two-thirds having a usual interstitial pneumonia-like pattern on HRCT. The primary endpoint is the annual rate of declin...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:BMJ Open Respir Res
Κύριοι συγγραφείς: Flaherty, Kevin R, Brown, Kevin K, Wells, Athol U, Clerisme-Beaty, Emmanuelle, Collard, Harold R, Cottin, Vincent, Devaraj, Anand, Inoue, Yoshikazu, Le Maulf, Florence, Richeldi, Luca, Schmidt, Hendrik, Walsh, Simon, Mezzanotte, William, Schlenker-Herceg, Rozsa
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BMJ Publishing Group 2017
Θέματα:
Interstitial Lung Disease
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604725/
https://ncbi.nlm.nih.gov/pubmed/29018526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjresp-2017-000212
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