Llwytho...

Methotrexate and low-dose prednisolone downregulate osteoclast function by decreasing receptor activator of nuclear factor-κβ expression in monocytes from patients with early rheumatoid arthritis

OBJECTIVE: Rheumatoid arthritis (RA) is a systemic, immune-mediated inflammatory disease that ultimately leads to bone erosions and joint destruction. Methotrexate (MTX) slows bone damage but the mechanism by which it acts is still unknown. In this study, we aimed to assess the effect of MTX and low...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:RMD Open
Prif Awduron: Perpétuo, Inês Pedro, Caetano-Lopes, Joana, Rodrigues, Ana Maria, Campanilho-Marques, Raquel, Ponte, Cristina, Canhão, Helena, Ainola, Mari, Fonseca, João Eurico
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: RMD Open 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604603/
https://ncbi.nlm.nih.gov/pubmed/28955481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2016-000365
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