Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling

BACKGROUND: Meningiomas are the most common primary intracranial tumors in adults. While a majority of meningiomas are slow growing neoplasms that may cured by surgical resection, a subset demonstrates more aggressive behavior and insidiously recurs despite surgery and radiation, without effective a...

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Библиографические подробности
Опубликовано в: :Cell Commun Signal
Главные авторы: Mei, Yu, Du, Ziming, Hu, Changchen, Greenwald, Noah F., Abedalthagafi, Malak, Agar, Nathalie Y.R., Dunn, Gavin P., Bi, Wenya Linda, Santagata, Sandro, Dunn, Ian F.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604305/
https://ncbi.nlm.nih.gov/pubmed/28923059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-017-0189-7
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