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ADCC employing an NK cell line (haNK) expressing the high affinity CD16 allele with avelumab, an anti-PD-L1 antibody

NK-92 cells, and their derivative, designated aNK, were obtained from a patient with non-Hodgkin lymphoma. Prior clinical studies employing adoptively transferred irradiated aNK cells have provided evidence of clinical benefit and an acceptable safety profile. aNK cells have now been engineered to e...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Jochems, Caroline, Hodge, James W., Fantini, Massimo, Tsang, Kwong Y., Vandeveer, Amanda J., Gulley, James L., Schlom, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604238/
https://ncbi.nlm.nih.gov/pubmed/28477372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30767
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