tRNAs and proteins use the same import channel for translocation across the mitochondrial outer membrane of trypanosomes

Mitochondrial tRNA import is widespread, but the mechanism by which tRNAs are imported remains largely unknown. The mitochondrion of the parasitic protozoan Trypanosoma brucei lacks tRNA genes, and thus imports all tRNAs from the cytosol. Here we show that in T. brucei in vivo import of tRNAs requir...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Niemann, Moritz, Harsman, Anke, Mani, Jan, Peikert, Christian D., Oeljeklaus, Silke, Warscheid, Bettina, Wagner, Richard, Schneider, André
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2017
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604042/
https://ncbi.nlm.nih.gov/pubmed/28847952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711430114
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