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tRNAs and proteins use the same import channel for translocation across the mitochondrial outer membrane of trypanosomes

Mitochondrial tRNA import is widespread, but the mechanism by which tRNAs are imported remains largely unknown. The mitochondrion of the parasitic protozoan Trypanosoma brucei lacks tRNA genes, and thus imports all tRNAs from the cytosol. Here we show that in T. brucei in vivo import of tRNAs requir...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Niemann, Moritz, Harsman, Anke, Mani, Jan, Peikert, Christian D., Oeljeklaus, Silke, Warscheid, Bettina, Wagner, Richard, Schneider, André
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604042/
https://ncbi.nlm.nih.gov/pubmed/28847952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711430114
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