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Quantitative tests of a reconstitution model for RNA folding thermodynamics and kinetics

Decades of study of the architecture and function of structured RNAs have led to the perspective that RNA tertiary structure is modular, made of locally stable domains that retain their structure across RNAs. We formalize a hypothesis inspired by this modularity—that RNA folding thermodynamics and k...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bisaria, Namita, Greenfeld, Max, Limouse, Charles, Mabuchi, Hideo, Herschlag, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604005/
https://ncbi.nlm.nih.gov/pubmed/28839094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703507114
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