The Neurosteroidogenic Enzyme 5α-Reductase Mediates Psychotic-Like Complications of Sleep Deprivation

Acute sleep deprivation (SD) can trigger or exacerbate psychosis- and mania-related symptoms; the neurobiological basis of these complications, however, remains elusive. Given the extensive involvement of neuroactive steroids in psychopathology, we hypothesized that the behavioral complications of S...

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Bibliographic Details
Published in:Neuropsychopharmacology
Main Authors: Frau, Roberto, Bini, Valentina, Soggiu, Alessio, Scheggi, Simona, Pardu, Alessandra, Fanni, Silvia, Roncada, Paola, Puligheddu, Monica, Marrosu, Francesco, Caruso, Donatella, Devoto, Paola, Bortolato, Marco
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603808/
https://ncbi.nlm.nih.gov/pubmed/28102229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.13
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