Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk

MYCN amplification and 11q deletion are two inversely correlated prognostic factors of poor outcome in neuroblastoma. Here we identify common variants at 11q22.2 within MMP20 that associate with neuroblastoma cases harboring 11q deletion (rs10895322), using GWAS in 113 European-American cases and 51...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Chang, Xiao, Zhao, Yan, Hou, Cuiping, Glessner, Joseph, McDaniel, Lee, Diamond, Maura A., Thomas, Kelly, Li, Jin, Wei, Zhi, Liu, Yichuan, Guo, Yiran, Mentch, Frank D., Qiu, Haijun, Kim, Cecilia, Evans, Perry, Vaksman, Zalman, Diskin, Sharon J., Attiyeh, Edward F., Sleiman, Patrick, Maris, John M., Hakonarson, Hakon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603517/
https://ncbi.nlm.nih.gov/pubmed/28924153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00408-8
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