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Kinase inhibitor screening using artificial neural networks and engineered cardiac biowires

Kinase inhibitors are often used as cancer targeting agents for their ability to prevent the activation of cell growth and proliferation signals. Cardiotoxic effects have been identified for some marketed kinase inhibitors that were not detected during clinical trials. We hypothesize that more predi...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Conant, Genevieve, Ahadian, Samad, Zhao, Yimu, Radisic, Milica
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603510/
https://ncbi.nlm.nih.gov/pubmed/28924210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12048-5
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