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Kinase inhibitor screening using artificial neural networks and engineered cardiac biowires

Kinase inhibitors are often used as cancer targeting agents for their ability to prevent the activation of cell growth and proliferation signals. Cardiotoxic effects have been identified for some marketed kinase inhibitors that were not detected during clinical trials. We hypothesize that more predi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Conant, Genevieve, Ahadian, Samad, Zhao, Yimu, Radisic, Milica
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603510/
https://ncbi.nlm.nih.gov/pubmed/28924210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12048-5
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