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Retinoic acid, CYP26, and drug resistance in the stem cell niche

The bone marrow niche is essential for hematopoietic stem cells to maintain lifelong blood production, by balancing their self-renewal and differentiation. Hematologic malignancies have a similar hierarchical organization to their normal counterparts, with rare populations of cancer stem cells that...

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Detalhes bibliográficos
Publicado no:Exp Hematol
Main Authors: Alonso, Salvador, Jones, Richard J, Ghiaur, Gabriel
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603425/
https://ncbi.nlm.nih.gov/pubmed/28754309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2017.07.004
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