Circulating RANKL and RANKL/OPG and breast cancer risk by ER and PR subtype: Results from the EPIC cohort

Receptor activator of nuclear factor kappa-B (RANK)-RANK ligand (RANKL) signaling promotes mammary tumor development in experimental models. Circulating concentrations of soluble RANKL (sRANKL) may influence breast cancer risk via activation of RANK signaling; this may be modulated by osteoprotegeri...

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Published in:Cancer Prev Res (Phila)
Main Authors: Sarink, Danja, Schock, Helena, Johnson, Theron, Overvad, Kim, Holm, Marianne, Tjønneland, Anne, Boutron-Ruault, Marie-Christine, His, Mathilde, Kvaskoff, Marina, Boeing, Heiner, Lagiou, Pagona, Papatesta, Eleni-Maria, Trichopoulou, Antonia, Palli, Domenico, Pala, Valeria, Mattiello, Amalia, Tumino, Rosario, Sacerdote, Carlotta, Bueno-de-Mesquita, H.B(as), van Gils, Carla H, Peeters, Petra H, Weiderpass, Elisabete, Agudo, Antonio, Sánchez, Maria-José, Chirlaque, Maria-Dolores, Ardanaz, Eva, Amiano, Pilar, Khaw, Kay Tee, Travis, Ruth, Dossus, Laure, Gunter, Mark, Rinaldi, Sabina, Merritt, Melissa, Riboli, Elio, Kaaks, Rudolf, Fortner, Renée T.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603271/
https://ncbi.nlm.nih.gov/pubmed/28701332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-17-0125
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