Recombinant Vaccinia Viruses Coding Transgenes of Apoptosis-Inducing Proteins Enhance Apoptosis But Not Immunogenicity of Infected Tumor Cells

Genetic modifications of the oncolytic vaccinia virus (VV) improve selective tumor cell infection and death, as well as activation of antitumor immunity. We have engineered a double recombinant VV, coding human GM-CSF, and apoptosis-inducing protein apoptin (VV-GMCSF-Apo) for comparing with the earl...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biomed Res Int
Prif Awduron: Koval, Olga, Kochneva, Galina, Tkachenko, Anastasiya, Troitskaya, Olga, Sivolobova, Galina, Grazhdantseva, Antonina, Nushtaeva, Anna, Kuligina, Elena, Richter, Vladimir
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Hindawi 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603130/
https://ncbi.nlm.nih.gov/pubmed/28951871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3620510
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