IGF1 and NRG1 Enhance Proliferation, Metabolic Maturity, and the Force-Frequency Response in hESC-Derived Engineered Cardiac Tissues

Insulin-like growth factor 1 (IGF1) and neuregulin-1β (NRG1) play important roles during cardiac development both individually and synergistically. In this study, we analyze how 3D cardiac tissue engineered from human embryonic stem cell- (hESC-) derived cardiomyocytes and 2D-plated hESC-cardiomyocy...

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Vydáno v:Stem Cells Int
Hlavní autoři: Rupert, Cassady E., Coulombe, Kareen L. K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603111/
https://ncbi.nlm.nih.gov/pubmed/28951744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7648409
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