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Ornithine uptake and the modulation of drug sensitivity in Trypanosoma brucei
Trypanosoma brucei, protozoan parasites that cause human African trypanosomiasis (HAT), depend on ornithine uptake and metabolism by ornithine decarboxylase (ODC) for survival. Indeed, ODC is the target of the WHO “essential medicine” eflornithine, which is antagonistic to another anti-HAT drug, sur...
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| Publicado no: | FASEB J |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5602898/ https://ncbi.nlm.nih.gov/pubmed/28679527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700311R |
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