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Targeted inhibition of the phosphoinositide 3-kinase impairs cell proliferation, survival, and invasion in colon cancer

BACKGROUND: Colon cancer is the third most common cancer in the world, and its metastasis and drug resistance are challenging for its effective treatment. The PI3K/Akt/mTOR pathway plays a crucial role in the pathogenesis of colon cancer. The aim of this study was to investigate the targeting of PI3...

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Dettagli Bibliografici
Pubblicato in:Onco Targets Ther
Autori principali: Yang, Fei, Gao, Jun-Yi, Chen, Hua, Du, Zhen-Hua, Zhang, Xue-Qun, Gao, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602681/
https://ncbi.nlm.nih.gov/pubmed/28979133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S145601
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