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Distinct Pathways of Desensitization of A(1)- and A(2)-Adenosine Receptors in DDT(1) MF-2 Cells

Desensitization of adenosine receptors (ARs) was studied in DDT(1) MF-2 cells, which possess both A(1)- and A(2)AR, differentially coupled to adenylate cyclase. (−)-N(6)-(R)-Phenylisopropyladenosine (R-PIA), an A(1)AR-selective agonist at the appropriate concentrations, desensitized A(1)AR-mediated...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Ramkumar, Vickram, Olah, Mark E., Jacobson, Kenneth A., Stiles, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602552/
https://ncbi.nlm.nih.gov/pubmed/1944235
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