Modelling the drivers of the spread of Plasmodium falciparum hrp2 gene deletions in sub-Saharan Africa

Rapid diagnostic tests (RDTs) have transformed malaria diagnosis. The most prevalent P. falciparum RDTs detect histidine-rich protein 2 (PfHRP2). However, pfhrp2 gene deletions yielding false-negative RDTs, first reported in South America in 2010, have been confirmed in Africa and Asia. We developed...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Watson, Oliver J, Slater, Hannah C, Verity, Robert, Parr, Jonathan B, Mwandagalirwa, Melchior K, Tshefu, Antoinette, Meshnick, Steven R, Ghani, Azra C
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2017
Matèries:
Epidemiology and Global Health
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602420/
https://ncbi.nlm.nih.gov/pubmed/28837020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25008
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