p53R2 overexpression in cervical cancer promotes AKT signaling and EMT, and is correlated with tumor progression, metastasis and poor prognosis

p53R2 is a p53-inducible ribonucleotide reductase subunit involved in deoxyribonucleotide biosynthesis and DNA repair. Although p53R2 has been linked to human cancer, its role in cervical cancer remains unknown. In this study, we investigated the expression and clinical significance of p53R2 in earl...

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Dettagli Bibliografici
Pubblicato in:Cell Cycle
Autori principali: Jiang, Chao, Xu, Rui, Li, Xiao-Xing, Wang, Yan-Yan, Liang, Wen-Qian, Zeng, Ju-Deng, Zhang, Shan-Shan, Xu, Xiao-Yi, Yang, Yang, Zhang, Mei-Yin, Wang, Hui-Yun, Zheng, X. F. Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
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Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602298/
https://ncbi.nlm.nih.gov/pubmed/28841361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1320629
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