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Programmed death-ligand 1 (PD-L1) expression in tumour cell and tumour infiltrating lymphocytes of HER2-positive breast cancer and its prognostic value

Immunotherapy targeting PD-1/PD-L1 axis showed benefits in cancer. Prognostic significance of tumour infiltrating lymphocytes (TILs) has been determined. We evaluated PD-L1 protein expression in tumour cells and TILs, PD-L1 mRNA level and various histopathologic factors including TILs using 167 form...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Kim, Ahrong, Lee, So Jeong, Kim, Young Keum, Park, Won Young, Park, Do Youn, Kim, Jee Yeon, Lee, Chang Hun, Gong, Gyungyub, Huh, Gi Yeong, Choi, Kyung Un
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601941/
https://ncbi.nlm.nih.gov/pubmed/28916815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11905-7
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