Mifepristone inhibits ovarian cancer metastasis by intervening in SDF-1/CXCR4 chemokine axis

SDF-1/CXCR4 signaling axis determines the proliferative potential and site-specific cancer metastasis. Recent studies suggest involvement of the axis and steroidal hormone in ovarian cancer metastasis. Here we hypothesize that mifepristone (RU486), a well-known progesterone-based abortifacient, migh...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zheng, Ning, Chen, Jiahang, Liu, Weiqun, Liu, Jian, Li, Tao, Chen, Hongning, Wang, Jichuang, Jia, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601719/
https://ncbi.nlm.nih.gov/pubmed/28938623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19289
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