Genistein up-regulates miR-20a to disrupt spermatogenesis via targeting Limk1

Genistein (GEN) is one of the isoflavones that has effect on male reproduction. However, the underlying mechanism remains unknown. miRNAs are a type of small non-coding RNAs that play important roles in spermatogenesis. We measured the GEN levels and miR-17-92 cluster expression in infertile subject...

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Detalhes bibliográficos
Publicado no:Oncotarget
Principais autores: Gu, Hao, Wu, Wei, Yuan, Beilei, Tang, Qiuqin, Guo, Dan, Chen, Yiqiu, Xia, Yankai, Hu, Lingqing, Chen, Daozhen, Sha, Jiahao, Wang, Xinru
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601687/
https://ncbi.nlm.nih.gov/pubmed/28938591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17637
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