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Amisulpride augmentation in clozapine-unresponsive schizophrenia (AMICUS): a double-blind, placebo-controlled, randomised trial of clinical effectiveness and cost-effectiveness.

BACKGROUND: When treatment-refractory schizophrenia shows an insufficient response to a trial of clozapine, clinicians commonly add a second antipsychotic, despite the lack of robust evidence to justify this practice. OBJECTIVES: The main objectives of the study were to establish the clinical effect...

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Detalhes bibliográficos
Publicado no:Health Technol Assess
Main Authors: Barnes, Thomas Re, Leeson, Verity C, Paton, Carol, Marston, Louise, Davies, Linda, Whittaker, William, Osborn, David, Kumar, Raj, Keown, Patrick, Zafar, Rameez, Iqbal, Khalid, Singh, Vineet, Fridrich, Pavel, Fitzgerald, Zachary, Bagalkote, Hemant, Haddad, Peter M, Husni, Mariwan, Amos, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: NIHR Journals Library 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601255/
https://ncbi.nlm.nih.gov/pubmed/28869006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3310/hta21490
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